I started this project after coming across an article discussing the development of different morphine-like compounds that would alleviate pain, but avoid the negative side effects such as drug tolerance and drug dependency.
This is a small side element that I put together.
Structure-based Discovery of Opioid Analgesics with Reduced Side Effects Aashish Manglik, et al. Nature 537, 185–190 (08 September 2016) doi:10.1038/nature19112